NFL odds courtesy of BetMGM Sportsbook. Odds updated Monday at 6:21 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub. Game time: 8:15 p.m. ET on Monday, Nov. 10

USA Today's NFL experts make their picks for a Week 10 showdown between the Indianapolis Colts and Atlanta Falcons

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 on a 52-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Both teams have been excellent for bettors, as well. The Rams and Seahawks are 11-3 SU/10-4 ATS, sharing the best spread-covering record in the NFL. So something’s got to give in this 8:15 p.m. ET Thursday meeting.

USA Today's NFL experts make their picks for a Week 10 showdown between the New York Jets and Cleveland Browns

NFL Week 16 features a full 16-game slate, including a number of key divisional matchups. In an important NFC North battle on Saturday, the

Week 15 had seismic repercussions for the playoffs and this week's odds. Check out the winners and losers so far.

The 2025-26 NFL regular season is heading into the stretch run, and Week 14 saw the Kansas City Chiefs potentially run out of time to make the postseason, after a 20-10 loss to the Houston Texans on Sunday Night Football pushed them to 6-7 on the season.

A few crucial Week 16 contests could impact division races, and potentially, playoff seeding. See the latest odds.